fap assay kit Search Results


fluorogenic fap assay kit  (BPS Bioscience)
93
BPS Bioscience fluorogenic fap assay kit
In vitro binding and specificity <t>of</t> <t>QCP01</t> and [111In]QCP02. (A) Cells incubated with various concentrations (range: 50–0.78 nM) of QCP01 were imaged with the LI-COR Pearl Impulse Imager to assess binding of the agent in various <t>FAP-positive</t> (+) and FAP-negative (−) cell lines (left). Dose–response curves of QCP01 binding in FAP-positive cell lines (NCIH2228, U87, and SKMEL24) and FAP-negative cell lines (PC3, NCIH226, and HCT116) were generated (right). (B) Cells were incubated with 0.037 MBq [111In]QCP02 and were washed with cold phosphate-buffered saline (PBS). The radioactivity of the cell pellets was measured and normalized to the incubated dose; ****, P < 0.0001. (C) Cells incubated with 25 nM QCP01 were incubated with various concentrations of either a DPP-IV and FAP inhibitor, Val-boroPro, or a DPPIV-only inhibitor, sitagliptin. The binding of QCP01 was measured, and semi-log inhibitor–response curves were generated for both Val-boroPro (left) and sitagliptin (right).
Fluorogenic Fap Assay Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/fluorogenic fap assay kit/product/BPS Bioscience
Average 93 stars, based on 1 article reviews
fluorogenic fap assay kit - by Bioz Stars, 2026-03
93/100 stars
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human picokine elisa kit  (Boster Bio)
93
Boster Bio human picokine elisa kit
In vitro binding and specificity <t>of</t> <t>QCP01</t> and [111In]QCP02. (A) Cells incubated with various concentrations (range: 50–0.78 nM) of QCP01 were imaged with the LI-COR Pearl Impulse Imager to assess binding of the agent in various <t>FAP-positive</t> (+) and FAP-negative (−) cell lines (left). Dose–response curves of QCP01 binding in FAP-positive cell lines (NCIH2228, U87, and SKMEL24) and FAP-negative cell lines (PC3, NCIH226, and HCT116) were generated (right). (B) Cells were incubated with 0.037 MBq [111In]QCP02 and were washed with cold phosphate-buffered saline (PBS). The radioactivity of the cell pellets was measured and normalized to the incubated dose; ****, P < 0.0001. (C) Cells incubated with 25 nM QCP01 were incubated with various concentrations of either a DPP-IV and FAP inhibitor, Val-boroPro, or a DPPIV-only inhibitor, sitagliptin. The binding of QCP01 was measured, and semi-log inhibitor–response curves were generated for both Val-boroPro (left) and sitagliptin (right).
Human Picokine Elisa Kit, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human picokine elisa kit/product/Boster Bio
Average 93 stars, based on 1 article reviews
human picokine elisa kit - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
lynch-fap devyser kit  (Devyser AB)
90
Devyser AB lynch-fap devyser kit
In vitro binding and specificity <t>of</t> <t>QCP01</t> and [111In]QCP02. (A) Cells incubated with various concentrations (range: 50–0.78 nM) of QCP01 were imaged with the LI-COR Pearl Impulse Imager to assess binding of the agent in various <t>FAP-positive</t> (+) and FAP-negative (−) cell lines (left). Dose–response curves of QCP01 binding in FAP-positive cell lines (NCIH2228, U87, and SKMEL24) and FAP-negative cell lines (PC3, NCIH226, and HCT116) were generated (right). (B) Cells were incubated with 0.037 MBq [111In]QCP02 and were washed with cold phosphate-buffered saline (PBS). The radioactivity of the cell pellets was measured and normalized to the incubated dose; ****, P < 0.0001. (C) Cells incubated with 25 nM QCP01 were incubated with various concentrations of either a DPP-IV and FAP inhibitor, Val-boroPro, or a DPPIV-only inhibitor, sitagliptin. The binding of QCP01 was measured, and semi-log inhibitor–response curves were generated for both Val-boroPro (left) and sitagliptin (right).
Lynch Fap Devyser Kit, supplied by Devyser AB, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/lynch-fap devyser kit/product/Devyser AB
Average 90 stars, based on 1 article reviews
lynch-fap devyser kit - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


In vitro binding and specificity of QCP01 and [111In]QCP02. (A) Cells incubated with various concentrations (range: 50–0.78 nM) of QCP01 were imaged with the LI-COR Pearl Impulse Imager to assess binding of the agent in various FAP-positive (+) and FAP-negative (−) cell lines (left). Dose–response curves of QCP01 binding in FAP-positive cell lines (NCIH2228, U87, and SKMEL24) and FAP-negative cell lines (PC3, NCIH226, and HCT116) were generated (right). (B) Cells were incubated with 0.037 MBq [111In]QCP02 and were washed with cold phosphate-buffered saline (PBS). The radioactivity of the cell pellets was measured and normalized to the incubated dose; ****, P < 0.0001. (C) Cells incubated with 25 nM QCP01 were incubated with various concentrations of either a DPP-IV and FAP inhibitor, Val-boroPro, or a DPPIV-only inhibitor, sitagliptin. The binding of QCP01 was measured, and semi-log inhibitor–response curves were generated for both Val-boroPro (left) and sitagliptin (right).

Journal: Journal of medicinal chemistry

Article Title: Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules

doi: 10.1021/acs.jmedchem.0c02171

Figure Lengend Snippet: In vitro binding and specificity of QCP01 and [111In]QCP02. (A) Cells incubated with various concentrations (range: 50–0.78 nM) of QCP01 were imaged with the LI-COR Pearl Impulse Imager to assess binding of the agent in various FAP-positive (+) and FAP-negative (−) cell lines (left). Dose–response curves of QCP01 binding in FAP-positive cell lines (NCIH2228, U87, and SKMEL24) and FAP-negative cell lines (PC3, NCIH226, and HCT116) were generated (right). (B) Cells were incubated with 0.037 MBq [111In]QCP02 and were washed with cold phosphate-buffered saline (PBS). The radioactivity of the cell pellets was measured and normalized to the incubated dose; ****, P < 0.0001. (C) Cells incubated with 25 nM QCP01 were incubated with various concentrations of either a DPP-IV and FAP inhibitor, Val-boroPro, or a DPPIV-only inhibitor, sitagliptin. The binding of QCP01 was measured, and semi-log inhibitor–response curves were generated for both Val-boroPro (left) and sitagliptin (right).

Article Snippet: The inhibitory activities of QCP01 and [ 113/115 In] QCP02 were determined using a fluorogenic FAP Assay Kit (BPS Bioscience, San Diego, CA).

Techniques: In Vitro, Binding Assay, Incubation, Generated, Radioactivity

NIRF imaging of QCP01 in a tumor-bearing mouse. NOD/SCID mice bearing FAP-positive U87 (red) and FAP-negative PC3 (white) tumor xenografts (n = 4) were injected with 5 nmol of QCP01 via the tail vein, followed by serial NIRF imaging on the LI-COR Pearl Impulse Imager. Representative images of QCP01 full body (left) distribution at 5 h after injection and organ-specific (right) distribution at 5, 24, and 48 h after injection are shown.

Journal: Journal of medicinal chemistry

Article Title: Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules

doi: 10.1021/acs.jmedchem.0c02171

Figure Lengend Snippet: NIRF imaging of QCP01 in a tumor-bearing mouse. NOD/SCID mice bearing FAP-positive U87 (red) and FAP-negative PC3 (white) tumor xenografts (n = 4) were injected with 5 nmol of QCP01 via the tail vein, followed by serial NIRF imaging on the LI-COR Pearl Impulse Imager. Representative images of QCP01 full body (left) distribution at 5 h after injection and organ-specific (right) distribution at 5, 24, and 48 h after injection are shown.

Article Snippet: The inhibitory activities of QCP01 and [ 113/115 In] QCP02 were determined using a fluorogenic FAP Assay Kit (BPS Bioscience, San Diego, CA).

Techniques: Imaging, Injection

Serial SPECT-CT imaging of [111In]QCP02 in a tumor-bearing mouse. A NOD/SCID mouse bearing FAP-positive U87 (red) and FAP-negative PC3 (blue) tumor xenografts was injected with 7.4 MBq [111In]QCP02 via the tail vein, followed by serial SPECT-CT imaging. Representative three-dimensional SPECT-CT images at various time points after injection (1, 3, 6, 10, and 28 h) are shown.

Journal: Journal of medicinal chemistry

Article Title: Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules

doi: 10.1021/acs.jmedchem.0c02171

Figure Lengend Snippet: Serial SPECT-CT imaging of [111In]QCP02 in a tumor-bearing mouse. A NOD/SCID mouse bearing FAP-positive U87 (red) and FAP-negative PC3 (blue) tumor xenografts was injected with 7.4 MBq [111In]QCP02 via the tail vein, followed by serial SPECT-CT imaging. Representative three-dimensional SPECT-CT images at various time points after injection (1, 3, 6, 10, and 28 h) are shown.

Article Snippet: The inhibitory activities of QCP01 and [ 113/115 In] QCP02 were determined using a fluorogenic FAP Assay Kit (BPS Bioscience, San Diego, CA).

Techniques: Single Photon Emission Computed Tomography, Imaging, Injection